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While these studies suggest that GLP-1 influx into the brain might be a GLP-1R-independent process with passive diffusion of GLP-1 through the BBB [[750], [751], [752]], other studies suggest that uptake of liraglutide into the brain is GLP-1R-dependent [686,753]

13:321-332 [PubMed: 39961315] 253

The general class of GLP-1 drugs targets at least one of the reactions

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