could glp-1 be the next mental health drug Impact of Receptor Agonists (GLP-1 RAs) on Health: A Systematic Review | Current Treatment Options in Psychiatry Glucagon-like peptide-1 receptor agonists and

Metabolism (2016) 65(8):118395

However, semaglutide exerted broader effects, extending laterally and more deeply into the posterior ARH compared to liraglutide, potentially explaining its greater effectiveness in weight reduction (147)

Specifically, it was shown to potently stimulate insulin release in response to glucose, and to restrict glycemic excursion, beyond that of the GLP-1 albumin fusion composed of WT albumin, likely due to a higher concentration in plasma

143 In studies involving healthy individuals, a 28-day treatment with sitagliptin did not affect lymphocyte and T cell subsets, plasma chemokine/cytokine concentrations, or cytokine release upon stimulation of peripheral blood mononuclear cells

Co-medication analysis revealed 81 cases with antidepressants, antipsychotics, and benzodiazepines, which may be proxies of mental health comorbidities