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5b, Supplementary Fig

doi: 10.2147/DMSO.S312527

Several SURMOUNT studies in patients with obesity are ongoing ( In the SURPASS-1 study, which enrolled 705 non-target T2DM patients with diet and physical activity intervention, the efficacy, safety, and tolerability of tirzepatide and a placebo were compared

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

79 While the direct renoprotective mechanisms of GLP-1RAs are still under investigation, their ability to enhance natriuresis and suppress pathogenic angiotensin II production presents a valuable therapeutic strategy in HFpEF complicated by CKD