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It should document a BMI of 30 or higher (or 27-plus with a comorbidity like hypertension, type 2 diabetes, dyslipidemia, or sleep apnea), failed diet and exercise, and cardiovascular or metabolic risk

Healthcare professionals prescribing GLP-1 medicines should provide balanced information about theoretical risks based on animal studies whilst emphasising that human evidence is reassuring
Adults who have had difficulty losing weight through diet and exercise alone and are seeking medically supervised support for long-term weight management
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