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In summary, convergent evidence from both preclinical and clinical research underscores the capacity of GLP-1RAs to interact with neural circuits that govern reinforcement and motivation, networks that are also targeted by drugs of abuse

This means your medication is made in small batches under pharmacist supervision, allowing for flexibility in dosing and faster patient access

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If you are trying to decide between the two medications, understanding the differences in how they work is essential

NICE has issued guidance (TA923) recommending tirzepatide as an option for managing overweight and obesity within its licensed indication, subject to specific criteria including BMI thresholds and the presence of weight-related comorbidities