nejm semaglutide cardiovascular New in the May 29, 2025, issue of NEJM: Sotatercept in Pulmonary Arterial Hypertension (ZENITH phase 3 trial) https://nej.md/4iYkLbj Oral and Outcomes (SOUL trial) https://nej.md/4hHII5M Upadacitinib for Giant-Cell Arteritis Blockbuster Diabetes and Weight-Loss Drug
Description
Anal fissures are small tears or cuts in the mucosal lining, a thin and delicate lining, of the anus

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As weight loss medications such as Ozempic become increasingly popular, it's important to understand the potential side effects associated with these treatments

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This review describes the basic and clinical pharmacology of orally administered semaglutide
