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Additionally, they activate the AMPK pathway in liver cells, which promotes fatty acid oxidation and reduces lipid accumulation (lipogenesis), offering potential benefits for non-alcoholic fatty liver disease (NAFLD) (Zheng et al., 2024)

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15 Additionally, the 2019 guidelines issued by the European Society of Cardiology and the EASD suggest using GLP1 RA as initial therapy in patients with type 2 diabetes and cardiovascular disease or those at high risk of cardiovascular disease (no class recommendation)