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Also, the liver, gut, kidney, lung, testis or skin, and the vascular system, which includes the aorta and vein endothelial cells, GLP-1 can reduce the production of inflammatory cytokines, chemokines, and the infiltration of immune cells in the tissues (Drucker, 2016

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Genetic predispositions in GLP-1R and GIP-R pathways influence how individual patients respond