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Tan wass on the same page, telling MNT that: While these results unfortunately highlight the complexity of addressing Alzheimers pathology, it has been demonstrated that neuroinflammation and metabolic regulation are valid treatment approaches

But the connection goes deeper than insulin

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The heterogeneity among the studies in terms of dosing, clinical indications and baseline psychiatric status complicates interpretation, but preliminary evidence suggests modest antidepressant effects and potential therapeutic roles in eating and SUD

Statistical analysis We characterized the baseline characteristics of the combination and monotherapy groups by reporting frequency distributions (counts and percentages) for categorical variables and descriptive statistics (means and standard deviations [SDs]) for continuous variables