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D.WuJ.LuJ.NikonovS.et al (2023)

Tirzepatide activates both GLP-1 and GIP receptors, creating a dual pathway that often succeeds where single-pathway GLP-1 therapy reaches a ceiling

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Weight Loss: The average percent weight loss from patients starting weight after these 18 months at each maintenance dose was: - 15% weight loss from baseline body weight at the 5mg dose -19.5% weight loss from baseline body weight at the 10mg dose -20.9% weight loss from baseline body weight at the 15mg dose (maximum dose) By contrast, the control group saw an average 3.1% weight loss compared to their baseline weight at 72 weeks

Ashley Toutounchis patients have wondered how Vyvanse compares to other treatments and whether its benefits outweigh the potential side effects