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Notably, the effectiveness and safety of lixisenatide are virtually not affected in moderate renal insufficiency patients [52]

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Freeze-thaw cycles can cause peptide aggregation and loss of potency

If a patient just doesnt want to continue weight loss medication, I would advise them to taper off the GLP-1 very slowly, while maximizing lifestyle changes, she notes

At these doses, you burn through a 5mg vial in about two weeks
