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Description
Given the role of vascular dysfunction with both myocardial dysfunction and impaired exercise capacity in HFpEF 54 , and the known expression of GLP-1 receptors in the vasculature, we hypothesized that the weight loss-independent actions of semaglutide in HFpEF might involve improved vascular function

This allows for a thorough and precise diagnosis
It mimics a naturally occurring hormone in the body called glucagon-like peptide-1 (GLP-1)

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Measuring inconsistency in meta-analyses
