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Based on the availability of baseline and at least one follow-up measurement, 320, 260, 155, 200, 155, and 297 patients were included in the analyses of HbA1c, body weight, TC, LDL, HDL, and BP, respectively

Notably, nearly 99% of participants remained free from diabetes at the 176-week mark

5-8 Clinical trials confirmed blood sugar benefits and showed that these medications also reduce risk of cardiovascular events in diabetics, including heart attack and stroke, by as much as 26%

It was reported that GLP-1R was expressed in colonic mucosal nerve fibers and showed increased expression in biopsies from individuals with IBS [55] (Fig
