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Crucially, the study included a calorie-restricted pair-fed group whose daily food intake was matched to the semaglutide group to isolate the effect of the drug from the effect of eating less

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That effect appears to be transient since after the 12-week treatment with exenatide no significant change of SEVR was detectable (43)

Because retatrutide has not yet received MHRA or EMA approval, it is not currently available through NHS prescriptions or licensed private clinics in the UK

J Pediatr 2003;143(3):372-376
