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The role of GLP-1 in appetite and weight regulation. Nature Metabolism

GLP-1 drugs mimic a natural hormone called glucagon-like peptide-1 , which helps regulate several metabolic functions in the body

One small crossover trial found that morning semaglutide injections before 8am produced roughly 15% lower post-prandial glucose compared to evening doses after 8pm

It is accessible only through participation in approved clinical trials

HYPOTHALAMIC CONTROL OF GLP-1 ACTIONS ON SATIATION AND SATIETY: ANIMAL STUDIES Various studies have focused on the hypothalamus as a target of different types of GLP-1R agonists
