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The slowing of gastric emptying means food remains in the stomach for longer periods before passing into the small intestine

Genetically predicted glucose-dependent Insulinotropic polypeptide (GIP) levels and Cardiovascular Disease Risk are driven by distinct causal variants in the GIPR Region

This slows down the digestion of food, which allows it to remain in the system longer and sends a longer-lasting signal to the brain that the body is full

Dado que la tirzepatida acta como un agonista dual de los receptores GIP y GLP-1, se cree que podra ofrecer beneficios adicionales al estimular mltiples hormonas endgenas implicadas en la regulacin energtica (Jastreboff et al., 2022)