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Pharmacokinetic actions of exendin-4 in the rat:comparison with glucagon-like peptide-1

There is some instances of gall bladder stones or inflammation of the glands around the stomach and small intestine

When blood sugar is too high (beyond what your body needs for energy) even more insulin is releasedand the body can take this as a sign to store the excess sugar as fat

Constipation adds to these troubles, because straining during a bowel movement increases pressure in the anal canal and pushes the hemorrhoids against the sphincter muscle