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Notably, persistent or new users of GLP-1 RAs exhibited better survival and kidney outcomes compared to ever users, with persistent users also showing superior MACEs and MAKEs outcomes

Laboratory and review evidence consolidated in two 2025 papers (Paschou IA et al, Endocrine 89(3):680-685, PMID 40498168

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Specifically, germline-less and feminized mutants live longer, the latter at certain temperatures, while masculinized mutants have shorter lifespans, indicating that fat accumulation alone does not ensure a longer life in reproductive deficient mutants

She took walks during her lunch break in an office park and regularly went to the gym