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Description
While offering a much-need treatment option for patients, this class of drugs rang alarm bells for payers once the budget impact was calculated at an annual cost of nearly $18,000, based on wholesale acquisition cost combined with an adult obesity prevalence rate of 41.9% in 2017 (National Health and Nutrition Examination Survey, 2020)

Daily fluctuations are normal on a GLP-1, especially after a step-up

PCR products were treated with 1 L Dpn1 (10 U/L) for 1 hour at 37C to digest parental DNA

In the meantime, some patients on long half-life GLPs are already stretching injections to every 1014 days , especially during maintenance phases

[DOI] [Google Scholar] Ma Y., Yang D., Ma Y., Zhang Y.-H
