soul trial oral semaglutide cardiovascular outcomes 2024 results nejm Reduces CV Events in T2DM – (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine 🧪 T2DM + ASCVD/CKD 💊 Oral semaglutide 14 mg vs placebo 📉 Forecasting Trial Milestones: A Predictive

These medications are especially helpful when diet and exercise alone are not sufficient

Reconstituting the drug in this manner creates a liquid solution, purportedly the equivalent of the brand-name drug, which can then be injected under the skin

Thats another reason theyre not going to see the long-term effects. Diede agreed that, at current prices, the economics are difficult to justify purely on cost savings

Furthermore, a meta-analysis of eight trials comparing semaglutide OW with SGLT2is found that semaglutide OW, at a dose of 1 mg, was significantly more effective in reducing weight and improving HbA1c than the SGLT2is evaluated (statistically meaningful at the 0.05 significance level) [20]

This fear can become paralyzing if left unchecked