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Utilization patterns of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus in Italy: a retrospective cohort study

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Promotes lipolysis and fat oxidation, making it one of the most potent peptides studied for body fat reduction

GLP-1 medications, such as semaglutide (known by brand names like Ozempic or Wegovy), are a class of drugs originally designed to treat type 2 diabetes

TRIUMPH-4, the first completed Phase 3 trial, showed 28.7% average body weight loss at 68 weeks on retatrutide 12mg versus 2.1% on placebo, as reported by Eli Lilly in December 2025 (peer-reviewed publication pending)