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Whilst declining beta-cell function is thought to generally reduce the response to incretins, GLP-1 appeared to be the more important incretin hormone in T2D (Nauck et al, 2021)
95% CI, 0.891.17), it was shown to be non-inferior to placebo in terms of cardiovascular safety (77)
Acute onset of neovascular age-related macular degeneration after initiation of tirzepatide
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