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Key data point: in the retatrutide fatty-liver study, Sanyal and colleagues (Nature Medicine, 2024) reported liver fat falling 80 to 90 percent over 48 weeks in patients who started with fatty liver disease, a drop tied closely to the weight and belly-fat loss and, in theory, to glucagon-receptor-driven fat burning in the liver

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PMC+1 What the human data show so far

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The Lancet, 389(10085), 22142225

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Trends Microbiol

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doi:10.1038/cr.2010.178 45

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