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These observations indicate that broadly applicable proteostasis impairments are a consequence of metabolite exposure
It is unclear whether GSH was either directly absorbed or broken down into its constituent amino acids and re-synthesized by glutathione synthetase
doi: 10.1111/j.1600-6143.2008.02359.x 10 Bugarski-KirolaD.NunezR.OdetallaR.LiuI
doi: 10.1016/S0016-5085(98)70644-4
HepG2, HT1080, and MEF cells were cultured in Dulbeccos modified Eagles medium (DMEM) supplemented with 10% fetal bovine serum (FBS) and 1% penicillin-streptomycin (P/S) at 37 C with 5% CO 2
