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Description
TLRs recognise and respond to a wide range of DAMPs, such as HMGB-1 and HSPs (Anders and Schaefer, 2014

taVNS involves the stimulation of the ABVN through contact with the external ear skin
Elevated nitric oxide (NO), reactive oxygen species (ROS), and pro-inflammatory cytokines (IL-1, TNF-, IFN-) further inhibit SLC7A11 and destabilize GPX4 activity in cancer cells

It also helps combat sun damage, improving skin tone and texture

For example, elevated ROS levels can trigger the assembly of NLRP3 inflammasomes, promote mPTP opening and initiate caspase-mediated apoptosis
