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Tissue distribution and stage-specific expression of HrGSTm1 The relative expression of HrGSTm1 in different tissues and developmental stages was detected by Real-time Quantitative polymerase chain reaction (qPCR)

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These effects have been correlated with steady reductions of cellular NAD + and ATP pools and the induction of necrosis, which could be prevented either by pharmacological inhibition or genetic deletion of PARP-1, as reviewed in Refs

Acanthosis Nigricans (AN) This is the most common cause
