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doi: 10.1165/ajrcmb.20.2.3305
In the chronic toxicity experiment, L-NAME caused severe tissue damage (myocardial and hepatic cell necrosis, necrosis of the lymphoid cells in the spleen) while L-arginine provoked predominantly congestion, edema and hemorrhages in all organs
This supports the need for novel therapeutic approaches
Then test
Pharmacokinetics and metabolism of dietary flavonoids in humans
