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Description
GPx4s anti-ferroptosis role is particularly fascinatingby curbing lipid peroxidation, it prevents iron-triggered cell death, relevant in brain injuries or cancers
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As such, this work is not considered to be human subject research
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Pharmacological inhibition of 12/15-LOX using agents such as ML351, LOXBlock-1, and BW-B70C significantly reduces infarct volume and mitigates poststroke brain damage (161163)
