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Description
It is called EAAT2 in humans (GLT-1 in mice) and is encoded by the SLC1A2 gene
Consists of 4 protein subunits and 3 iron-sulfer (Fe-S) clusters
About half of all cases of the disorder involve de novo NF1 mutations, which can be passed on to successive generations
Metabolic response in the late 72 h reperfusion time suggests that neural cells accelerate glutamate metabolic recovery to substitute the deprivation induced by ischemic event and presumably compensate for the altered synthetic function of damaged neural cells
Clodi K, Asgary Z, Zhao S, Kliche KO, Cabanillas F, Andreeff M , Younes A
