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Infective endocarditis caused by Streptococcus bovis resistant to the lethal effect of penicillin G

and disease/tissue injury processes, such as those involved in atherogenesis, drug toxicity, and ischemia-reperfusion injury

The mechanistic rationale is strong, the safety profile is established, and the observation that psoriatic arthritis patients have lower thymosin alpha-1 levels is suggestive

Experimental issues such as the selection of animals, volume of administration, use of anesthesia, and pH of the substance must be refined for the intranasal delivery

doi: 10.5402/2011/402647 221 XiongT.-T.LevequeT.AustruyA.GoixS.SchreckE.DappeV.et al