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The incidence of ALI/ARDS ranges from 1.5 to 100 per 100,000 person-years, depending on various factors, including methodology, geography, definition, age, and associated clinical disorders [3]

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This GHR upregulation sensitises local cells to circulating GH, potentiating GH-induced JAK2/STAT signalling and stimulating collagen matrix synthesis, IGF-1 production, and fibroblast proliferation providing a mechanism through which BPC-157 engages the GH/IGF-1 axis at the tissue level without altering systemic GH secretion