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The national library of medicine quotes a hypothesis that chronic, very low levels of vitamin B12 could be the cause of permanent, or at least refractory, changes in cognition and memory, which can lead to dementia

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Association between vitamin D and insulin resistance in adults with latent tuberculosis infection: Results from the National Health and Nutrition Examination Survey (NHANES) 20112012
Long-course radiotherapy in locally advanced rectal cancer: SHORT COURSE

doi: 10.1038/nature07201
