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Intraretinal oxygen levels before and after photoreceptor loss in the RCS rat

None of these mechanisms overlap

Puerarin-loaded PLGA were orally administered to Sprague-Dawley rats, where pharmacokinetic analysis showed a 10.52-fold increase in plasma bioavailability and a 6.46-fold increase in brain puerarin accumulation compared to oral administration of free puerarin

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Prevention of excessive ROS and repair of cellular damage are essential for the life of cells, and cells, in turn, contain many antioxidant systems to prevent the oxidative injury [60, 61]