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Your doctor or nurse will monitor you for signs of infusion-related reactions This type of passageknown as a fistulais an irregular connection from one part of the body to another and can sometimes be fatal Signs include headache, seizure, high blood pressure, sluggishness, confusion, and blindness In clinical studies across different types of cancer, some patients experienced the following side effects: Talk to your doctor if you are: Avastin should not be used for 28 days before or after surgery and until surgical wounds are fully healed Data have shown that Avastin may harm your unborn baby