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In addition, CKD is often associated with a variety of complications, such as mineral and bone disorders (MBD), and it is clinically recommended for regular vitamin D or vitamin D analogs and calcitriol treatment for MBD (Kidney Disease: Improving Global Outcomes, 20112017)

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Very frequent PVCs, estimated at 10,000 to 20,000 episodes a day, can weaken the heart muscle and increase the risk of heart failure if the condition isn't treated

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