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In women with diabetes, both oral and transdermal estrogen, with or without progestin, reduce fasting glucose, improve insulin resistance, and decrease LDL/high-density lipoprotein-cholesterol ratio (331)

CRLB was not used as the basis for exclusion of individual metabolites [52]

It took years to build up the sun damage that caused those discolourations, so it takes time to lessen their appearance