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The human leukocyte antigen (HLA) class II, cytotoxic T lymphocyte antigen-4 (CTLA-4) (on chromosome 2q33), protein tyrosine phosphatase non-receptor type 22 (PTPN22) (1p13), forkhead box P3 (FOXP3) (Xp 11), and interleukin 2 receptor (IL-2R) (10p15) are major genes found to contribute to a joint susceptibility for T1DM and AITD [29,31,32]
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Patients who supplement B12 during tirzepatide therapy commonly report better sustained energy levels compared to those who do not

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Note: If you need to change your injection day, you can do so as long as it has been at least 72 hours (3 days) since your last dose