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Finally, we would like to mention that the majority of the papers cited in this review were done in Professor Holmgren lab or by researchers that, for long or short period, visited his lab and remained fascinated by this small redoxin

In recent years, novel techniques have come to the fore that can help to facilitate accurate and practical assessment of iron balance

Acknowledgements This research was supported by the National Key R&D Program of China (2018YFC1313304, 2018YFC1313300), National Natural Science Foundation of China (81930065, 81871951), Natural Science Foundation of Guangdong Province (2019A1515010233, 2018B030306049), Pearl River S&T Nova Program of Guangzhou (201806010002), and CAMS Innovation Fund for Medical Sciences (CIFMS) (2019-I2M-5-036)

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Nakamura H, Nakamura K, Yodoi J: Redox regulation of cellular activation