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PLoS ONE 10 (11), e0142334
This potent NNMT inhibitor is a primary tool for laboratory research into metabolic rate regulation, cellular energy homeostasis, and adipocyte signaling pathways
The enhanced NAD+ availability and improved mitochondrial function in muscle cells may actually support muscle preservation and recovery, particularly when combined with resistance training and adequate protein intake
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In the animal models, inhibiting or knocking down NNMT improved markers tied to glucose handling and lowered cholesterol
