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This study reports that the enhanced relative treatment efficacy in Arg389 homozygotes occurs only at high doses (Parikh et al., 2018)

Detection principle: Reduced GSH can react with Dinitrobenzoic acid (DNTB) to form a yellow complex which can be detected by colorimetric assay at 405 nm and calculate the reduced GSH content indirectly
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Hangover symptoms were assessed using the Acute Hangover Scale (AHS) and Alcohol Hangover Severity Scale (AHSS) at various intervals post-alcohol consumption