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903 In a RANKL-induced osteoclast model, the bisphosphonate zoledronic acid promotes ferroptosis by increasing Fe 2+ , ROS, and MDA levels, and decreasing GPX4 and GSH levels

NAD+ Nicotinamide Adenine Dinucleotide (NAD+) is a co-enzyme derived from vitamin B3, signal molecule, and a novel neurotransmitter that is present in every cell in the body

Angiotensin II can be cleaved by another membrane-bound Zn 2+ -dependent peptidase (glutamyl aminopeptidase, also known as aminopeptidase A), which removes one amino acid from the N-terminal end generating the heptapeptide hormone angiotensin III (Arg-Val-Tyr-Ile-His-Pro-Phe)

Women with hormone-sensitive conditions should receive extra monitoring during treatment

For example, 'alanine, aspartate and glutamate metabolism' interacts widely with 'purine metabolism', 'pyrimidine metabolism' and 'histidine metabolism'