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This educational protocol presents a subcutaneous injection approach to maximize bioavailability from the 50 mg vial format

Oral AOD 9604 formulations exist but have significantly lower bioavailability than subcutaneous injection

In contrast, the 2,3-diamino substitution in the 1MQ scaffold (2,3-diamino-1MQ) displayed high passive permeability (Table 1), but moderate bi-directional active transport with moderate efflux ratio (Table 2)

Under proper storage conditions, an unopened bacteriostatic water vial will remain stable until its printed expiration date

References Thakral S, Sonje J, Munjal B, Bhatnagar B, Suryanarayanan R