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American Academy of Allergy Asthma and Immunology

The combination of a DPP-4 inhibitor with insulin is particularly attractive because it does not significantly increase the risk of hypoglycemia, as the insulin secretagogue effect is glucose-dependent

doi:10.1007/s40262-015-0343-6 64

Therefore, our initial investigation set out to provide a comprehensive analysis of the potency of tirzepatide at the mGIPR to identify potential limitations of using mouse models to study the actions of tirzepatide

These included age, race, ethnicity, breast density, highest BMI, and diabetes