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10.3389/fpsyt.2022.889636 108 NathanC.Cunningham-BusselA

Dissecting the association between gut microbiota and hypertrophic scarring: a bidirectional Mendelian randomization study

Jain N, Thompson PA, Burger JA, Ferrajoli A, Takahashi K, Estrov ZE, Borthakur G , Bose P, Kadia P, Pemmaraju N, Sasaki K, Garg N, Wang X, Kanagal-Shamanna R, Patel K, Jorgensen JL, Wang SA, Lopez W, Ayala A, Plunkett W, Gandhi V, Kantarjian H, O'Brien S, Keating MJ, and Wierda WG
Pediatr Diabetes 2004

The binding constant of GHK for copper (log10 = 16.44) slightly exceeds that of albumin (log10 = 16.2), enabling the peptide to acquire Cu2+ from plasma proteins and deliver it to cells while silencing coppers potentially damaging redox activity (Pickart, 1977)
