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undertook an open label RCT in which a monotherapy of 2000 g twice weekly B12 IM ( n = 50) was compared to daily administration of 10 mg oral nortriptyline ( n = 50)

This vitamin is excreted through bile, and is reabsorbed in the enterohepatic circulation

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IGFBP-1 regulates glucose levels through its effect on free IGF-1
