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Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

doi.org/10.3389/fphar.2021.627533 Regulatory Status FDA, WADA anti-doping, and compounding status provided for research context

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The evidence points to the involvement of NO in several features of the disease, such as bloodbrain barrier disruption, oligodendrocyte damage and demyelination, axonal degeneration, and loss of function as a result of reduced axonal conduction