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Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis
Fundamentals in Nasal Drug Delivery
10.1161/CIRCRESAHA.116.310477 61
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Overall, mounting evidence suggests that targeting CD38 and related NAD + -consuming enzymes, such as PARPs, has great potential as an NAD + -boosting target to extend human healthspan, and several pharmacological approaches are in development to inhibit CD38 and its NADase activity 232 (TABLE 1)
