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In fact, some different thiol-masking agents are routinely used to measure GSH and GSSG, such as alkylating agents (iodoacetic acid, NEM), 2-VP, 5-methyl methanethiosulfonate, monobromobimane [19]
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However, note that individual needs can vary, and an MTHFR variant doesnt necessarily mean you need supplementation or will benefit from it in the same way
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