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Of clinical significance to the role of ER-localized NADPH is that mutations in the H6PD gene are associated with glucocorticoid deficiency

Indeed, p62 is a versatile multifunctional protein that can cause opposite effects

IRI often surpasses the damage caused by ischemia alone (Cearra et al., 2021), and it has been extensively studied across various tissues and organs

The authors want to thank Anupa Wasti, Ranjeeta Odari, and other members of the Qiu Laboratory at the University of Mississippi for reading and discussing this book chapter during the manuscript preparation

Necroptosis: mechanisms and relevance to disease