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No enzymatic activity could be demonstrated to catalyze this reaction

Biomedical Simulations Resource, Los Angeles Beumer JH, Parise RA, Kanterewicz B, Petkovich M, DArgenio DZ, Hershberger PA (2012) A local effect of CYP24 inhibition on lung tumor xenograft exposure to 1,25-dihydroxyvitamin D(3) is revealed using a novel LC-MS/MS assay
It is also explored for mitigating damage from nonsteroidal anti-inflammatory drugs

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The mechanism operates through VEGFR2 receptor modulation
